Isotretinoin (Roaccutane): Key Questions Before You Start

When isotretinoin is used, how to take it correctly, and what you need to know about blood tests, pregnancy and dryness.

Isotretinoin (Roaccutane) is one of the most effective treatments for acne. It is prescribed for moderate to severe acne, or for acne that keeps coming back despite other treatments.

When does the doctor prescribe it?

• Inflamed spots or cysts under the skin that leave marks or scars
• Persistent acne despite creams and antibiotics
• Acne that is affecting your mood and self-confidence

How to take it correctly

• Take the capsule after a meal containing some fat so it is absorbed well, at the same time every day
• Monthly follow-up is important: the doctor adjusts the dose according to your response
• Blood tests (lipids and liver function) before starting and during treatment

What to avoid

• Pregnancy is strictly prohibited during treatment and for one month after it, and women have a pregnancy test every month
• Donating blood during treatment and for one month after it
• Waxing, laser and peeling during treatment and for up to 6 months after it
• Vitamin A supplements and certain antibiotics (tetracyclines) together with isotretinoin

Dryness is normal

Use a lip balm several times a day, a moisturizer for your face and body, and lubricating eye drops if needed. And sunscreen every day.

When to contact the doctor immediately

If you develop a severe headache with blurred vision, severe abdominal pain, or any change in mood, low mood, or disturbing thoughts.

This article is for awareness only and is not a substitute for a consultation.